2024 Undergraduate Exhibition
Title | Presenter | Abstract | Faculty Sponsor | Number | |
---|---|---|---|---|---|
Characterization and Bioinformatic Analysis of Related Vibriophages with ~42,000 bp Genomes from Chesapeake Bay | Emily Barrett |
Vibriophage are viruses that infect the marine bacterium Vibrio harveyi. A new cluster of vibriophages, Cluster B, were isolated from Chesapeake Bay oysters. These vibriophage are characterized by their shorter genome of ~42,000 bp, in comparison to the previously characterized Cluster A, which have genome lengths of ~126,000 bp. The genomes of these vibriophage were sequences and compared, and the lytic and lysogenic properties were analyzed. |
Gregory Broussard | 4 | |
Causative identification of Novel Polygenic Genes Associated with Obesity in Humans | Cole Caron |
For the past 40 years, humans have been seeing a significant increase in obesity. While a part of this is contributed to environment and monogenic obesity, polygenic obesity, where multiple genes affect the phenotype, is a more unexplored avenue of research. From a genome-wide association study, RUNX2 and TMEM151B have been correlated to an increase in obesity. These findings were then replicated in c. elegans to show that this correlative increase is causative of BMI increase. |
Melanie McReynolds | 110 | |
Categorizing the behavior of transgenic Alzheimer Disease zebrafish | Elle McGregor |
The aim of this project was to categorize anxiety, social, and cognitive behaviors in transgenic (Tg) Alzheimer Disease (AD) zebrafish to validate them as a viable model for AD. This was accomplished via light-dark, sociality, and novel object recognition tests that measured each behavior respectively. Anxiety and sociality behaviors in Tg fish deviated from predictions, while cognitive behaviors were consistent with predictions. These results create a foundation for future research involving these specific Tg fish. |
Cairsty Depasquale | 62 | |
Can a person anticipate what will happen next in English sentences during adverse conditions? | Yaquelyn Rivera and McKenzie Waslosky |
One way that humans can comprehend sentences is by anticipating or predicting upcoming words in the sentence. The present study builds on these findings to explore how people listen to and comprehend English sentences under conditions of babble versus silent background conditions using eye-tracking. Results show that under adverse speaking conditions, listeners find it more difficult to make predictions about upcoming input. |
Carrie Jackson | 40 | |
Bifidobacterium angulatum F16_22 Lipoprotein Structure, Acylation Patterns, and Toll-like Receptor Interaction | Matthew Masciulli |
This research investigates the lipoprotein structure of Bifidobacterium angulatum, and its implications for Toll-like Receptor interactions within the gut microbiome. Through lipoprotein extraction, we aim to extract and analyze the lipoprotein using mass spectrometry and western blot techniques. Our focus is on deciphering the unique structure and identifying the responsible gene, providing insight into innate immune responses. Outcomes may guide knowledge relating to probiotic and antibiotic strategies. |
Tim Meredith | 135 | |
Assessing the feasibility of biofiltration for methane reduction on Pennsylvania dairy farms | Vancie Peacock |
Biofilters, columns of support media colonized by methane oxidizing microbial communities, can be used to mitigate low-concentration methane. While pilot-scale biofilters show potential, little is known about their effectiveness when scaled for industrial use. Not enough research has been conducted on their environmental feasibility when scaled up to effectively put biofiltration to widespread use. We discovered that methane biofiltration may reduce total dairy farm emissions by 37% if applied to treat enteric and manure-related emissions. |
Juliana Vasco-Correa | 8 | |
Assessing the Effects of Heavy Metals and Salinity in Drinking Water on Skin Health | Zee Nguyen |
The existence of heavy metals and salinity in drinking water presents a considerable hazard to human health, particularly concerning dermatological concerns. This research explores the impacts of these heavy metals, in conjunction with salinity, on skin health and diseases in humans. This exposure leads to a range of dermatological issues, including skin lesions, hyperpigmentation, and even skin cancer. Despite being awareof the associated risks, many residents are unable to access alternative watersources. |
Asher Rosinger | 214 | |
Applying Cumulative Disadvantage Theory to Understand Adversity across the Lifespan and Later Life Inflammation | Saran Ashley-Douglas |
The theoretical perspectives of allostatic load and cumulative disadvantage can be used in tandem to consider the impact accumulated early and adult adversity has on health. We tested associations between early life and adulthood adversity on inflammation in the Einstein Aging Study (N = 205, Age Range = 70-89) with race as a moderator. Using regression and correlational models, significant effects were seen for adult/early life adversity and IL6, TNF- α, race modified associations. |
Jennifer Graham-Engeland | 72 | |
Analyzing the impact of well-being on false memories in adults | Desirae Mecca |
The current study aims to examine the role that physical and mental well-being plays in falsely remembering information in both younger and older adults. Participants completed 4 memory tasks and well-being measures. Whereas older adults had better mental well-being, younger adults had better physical well-being; however, well-being was not related to their likelihood of falsely remembering stimuli. Results suggest that well-being varies between age groups but is not related to false memories. |
Nancy Dennis | 64 | |
Analysis of Reversal Learning in Bluebirds | Gabriel Casanova |
Learning flexibility is vital to overcome challenges for survival. My experiment tested the learning flexibility in Bluebirds through a reversal learning puzzle by using a wooden trapdoor lever mechanism; switching the active lever’s location between left and right. I used BORIS software to measure the frequency and length of different bluebird and nestbox interactions. Information from analysis will help demonstrate the Bluebird’s environmental adaptability. |
Jason Keagy | 26 | |
An Inverse Problem for Epidemic Models | Chenxi Ma |
The first step of the project will be to understand the basic ideas of modeling as well as the simple theoretical arguments for the long-term behavior of the SIS model. Those arguments rely on a mix of explicit solutions, quantitative estimates, and the classical study of solutions in the neighborhood of steady states. As part of this first step, we implement numerical methods to illustrate the behavior of solutions to the deterministic SIS model.The final objective is to study an optimal control problem for an epidemic SIVS system. This model incorporates time-dependent and imperfect vaccination rates, which we attempt to optimize in terms of the balance of benefits-cost at the scale of the total population. |
Amina Amassad | 77 | |
An Exploration of the Effect of Triangulation on Children's Prosocial Development | Katia Fuller |
This poster reviews presently existing literature about triangulation, which in the field of human development and family studies refers to when two caregivers/parents are engaged in a conflict and they recruit one of their children to mediate, take a side, or offer their opinion. Of interest, I examine whether a child's triangulation exposure influences positive prosocial development and whether a triangulated child is empathetic towards peers. |
Gregory Fosco | 117 | |
Age-Specific Effects of NAD+ Precursors on Vitality in Caenorhabditis elegans | Shaina Johnson |
Nicotinamide Adenine Dinucleotide (NAD+), is an essential coenzyme to key metabolic pathway and declines with age. This phenomenon is associated with various hallmarks of aging and raises questions about supplementing declining NAD+ levels. Although NAD+ precursor supplementation has become popular in recent years, its impact remains poorly understood. Thus, this study investigates the impact of two NAD+ precursors that drive NAD+ synthesis in C. elegans: Nicotinic Acid (NA) and Nicotinamide (NAM). |
Melanie McReynolds | 218 | |
Adolescent anxiety and the role of parental support of child emotion regulation during COVID-19 pandemic | Jihee Lee |
Adolescence is a transitional period during which a child undergoes social and emotional changes, adding a layer of vulnerability to increased anxiety symptoms. The COVID-19 pandemic disrupted many lives, confining adolescents to their homes and inducing external stressors for parents. For this study, we found that less parental support of adolescents’ reappraisal was associated with higher levels of adolescent anxiety. This effect was more significant among families who were highly impacted by the pandemic. |
Sarah Myruski | 217 | |
Adenylosuccinate Lyase Plays a Role in Neuromuscular Coordination | Mia Peifer |
Adenylosuccinate Lyase (ADSL) Deficiency is a rare disorder associated with severe neuromuscular symptoms that arise from unknown mechanisms. Disruption of adsl-1 function in C. elegans results in a distinct inability to regulate body bend angles during swimming movement. We use this locomotive phenotype to study the role of adsl-1 in neuromuscular coordination. Our results suggest neuromuscular coordination could be regulated by adsl-1 in the neuron rather than in muscle, tyramine signaling, or energy production alone. |
Wendy Hanna-Rose | 57 | |
Adenlyosuccinate alleviates mobility deficits associated with Adenylosuccinate Synthetase deficiency in Caenorhabditis elegans | Melinda Jin and Rishika Patil |
ADSSL1-Myopathy is an ultra-rare muscular disorder caused by a mutation in the purine nucleotide cycle (PNC) gene, ADSSL1. ADSSL1-Myopathy had been hard to characterize on a molecular level due to a lack of adequate models for its study. We are investigating the functions of ADSS using C. elegans and are exploring the use of PNC substrates as a potential therapy. We have established movement phenotypes associated with ADSS function that can be rescued by adenylosuccinate. |
Wendy Hanna-Rose | 38 | |
Addressing Inequities in Biking Among Children: A Qualitative Study with Traffic Gardens | Imanirose Carter |
A traffic garden is a designed space where children can learn traffic laws and bike safety in a controlled environment, often located in parks or schools that connect the community. Research was done by interviewing traffic garden (n=13 ) organizers from different communities and then transcribing and coding for relevant themes. Results showed traffic gardens serve as learning environments and help underserved communities by addressing inequities by providing access to safe spaces and biking resources. |
Melissa Bopp | 150 | |
Abiotic Factors Affecting Microstegium Vimineum Populations in Rothrock State Forest | Joseph Lofland |
Microstegium vimineum (microstegium), also known as Japanese Stiltgrass, is an invasive grass that plagues Pennsylvania forests. Microstegium outcompetes native speacies to decrease species biodiversity and available foodstocks for wildlife. Previous studies in Pennsylvania have examined prevention and other studies in different parts of the U.S. have described factors affecting that area. None have discussed the specific factors leading to the population densities found in Rothrock State Forest. Data was obtained in association with the Deer Forest Project. Field measured values as well as GIS calculations were used. Results will be discussed further. |
Patrick Drohan | 203 | |
A Spectroscopic Study of the Peculiar Planetary Nebula Abell 57 | Akshat Chaturvedi |
The Galactic planetary nebula Abell 57 (PN G058.6+06.1) is theorized to be a member of the rare and poorly understood class of 'EGB-6 type' planetary nebula nuclei. We present an analysis of a Hobby-Eberly Telescope LRS II spectrum of Abell 57 to confirm its membership in this poorly understood class of objects. We find it to contain a compact emission knot similar to EGB-6. |
Howard Bond | 102 | |
A Smarter Mirror for a Smarter Student: Designing a Smart Mirror for Student Productivity and Well-Being | Carolyn 'Tomi' Oluwaseun-Apo |
The goal to improve well-being for Penn State students initiated an explorative research study into smart mirror design and its current integration in student’s daily activities. This study is inspired by a multi-stage framework to achieve a healthy lifestyle through technology. The study was informed by both a university-wide survey and cognitive walkthroughs of the mirror prototype. Findings include design considerations for balancing student interest in cognitive load and challenging users to engage in self-improvement. |
Chris Gamrat | 147 | |
A Performance of Two Spirituals: 'Is there anybody here that loves my Jesus' and 'I want Jesus to walk with me' | Thomas Delahoy |
My performance consists of two spirituals. The first is 'I want Jesus to walk with me' arranged by Undine Smith Moore and the second is 'Is there anybody here that loves my Jesus' arranged by Norah Duncan. In the first spiritual, the character is sorrowful and longing for a connection to anyone who loves God. The second spiritual is a call to Jesus himself. This character longs for Jesus’ help in the trials of life. |
Jennifer Trost | 78 | |
A New Era: Social Media and the Rise of Populism | Benjamin Woolsey |
This question of why some people possess populist attitudes and others don’t, will be explored through survey research. A survey was distributed through Meta advertisements in order to reach social media users directly. Respondents were asked a variety of questions regarding their social media use, such as how long they use social media, how often they use it for news, and to gauge their political participation through commenting and reposting. Afterwards they are then asked a variety of questions gauging different populist attitudes as established by current literature. |
Marie Hojnacki | 10 | |
A High-Throughput Computational Pipeline that Identifies Active, Small Self-Cleaving Ribozymes Riddled with Imperfections | Benjamin Chang |
Twister, twister sister, and hammerhead are small self-cleaving ribozymes that cleave their phosphodiester backbone and are defined by unique structures. By combining multiple RNA computational tools with customized scripts, I created a pipeline capable of searching through numerous genomes for these three ribozymes simultaneously. We identified over 800 novel ribozyme candidates in over 50 organisms. From these, we experimentally tested our top candidates and confirmed the first active twister ribozyme in a mammal, the dolphin. |
Philip Bevilacqua | 52 | |
3D-4-BigData: 3D Printed Electronics enabled 4D Visualization of Big Data Networks | Julian Kim |
Current statistical/computational advances in network analysis lack the ability to understand the interconnectedness between network nodes in a tactile manner. The overall research goal is to design-develop-demonstrate-evaluate a novel data visualization method that brings together data analytics, augmented reality (AR), and 3D Printed Electronics (3DPE). Our approach can yield novel image-derived phenotype (IDP) biomarkers for complex diseases as well as provide pleiotropic gene targets for drug repurposing. |
Guhaprasanna Manogharan | 143 | |
3D GR-MHD Simulations | Harshraj Bandyopadhyay |
I present the results of 3D general-relativistic magnetohydrodynamic simulations of the differentially rotating neutron stars performed with GR-Athena++. We study the magnetorotational instability and the turbulence it induces by looking at distinct patterns in the magnetic field, and the interaction between this field and the fluid respectively. Additionally, we measure the effective shear viscosity in order to calibrate future simulations, and finally we compare our results with 2D simulations in the literature. |
David Radice | 83 | |
'Examining the physical, social, and risk-related consequences of alcohol use as predictors of alcohol use disorder symptoms among college students' | Alyssa Altstaedter et al |
College students' alcohol use is a public health concern with physical, social, and risk-related consequences. Consequences like hangovers, unwanted sexual situations, and embarrassing oneself may be associated with alcohol use disorder (AUD) symptoms. Electronic surveys spanning six weekends assessed college students' (N= 462, 51.7% female, 87.7% White, Mage= 20.1) drinking behaviors and consequences. This project uses linear regression analysis to examine the extent to which alcohol-related consequences are associated with AUD symptoms among college students. |
Robert Turrisi | 42 | |
'Dying/Newborn': The Winter's Tale as Dramaturgical Theory | Arushi Grover |
This project follows efforts to revive Shakespeare’s The Winter’s Tale with a post-COVID focus on time and grief. The play’s production and adaptation history prove continuous reinterpretation across time. Two original attempts at adapting the play demonstrate Jane Barnette’s theory of “adapturgy†|
Elizabeth Bonjean | 189 | |
'Anne Boleyn' from Try Me Good King: Last Words of the Wives of Henry VIII by Libby Larsen | Sarah Esslinger |
Written by contemporary American composer Libby Larsen, Try Me, Good King recounts the final words of the wives of King Henry VIII. The songs explore the Queens' final thoughts and emotions as they approach death. The text in 'Anne Boleyn' is derived from three sources: a letter that Anne wrote to Henry VIII, two letters that Henry VIII wrote to Anne, and Anne's speech at her execution on May 19, 1536. |
Rachel E. Copeland | 193 |