I am a third-year Biochemistry and Molecular Biology major at the University Park campus. I am an undergraduate researcher in the Hanna-Rose lab where I study Inborn Errors of Purine Metabolism in the nematode C. elegans. My project aims to use C. elegans to investigate the molecular mechanisms responsible for the neuromuscular phenotypes associated with ADSSL1-Myopathy, a rare muscular disorder.
I can provide assistance with identifying research interests and contacting potential faculty mentors. I am also happy to assist with applications for the Erickson Discovery Grant, BMB Summer Undergraduate Research Fellowship, and REU/SURF programs.
Project Title:
Investigating Phenotypes Associated with Perturbations in Adenylosuccinate Synthetase Function in Caenorhabditis elegans
Project Description:
My project aims to provide a more in-depth understanding of the functions of ADSS, an enzyme in the purine nucleotide cycle, whose genetic mutation is responsible for causing ADSSL-1 Myopathy, a rare muscular disorder. ADSSL1-Myopathy has not been characterized on a molecular level due to a lack of adequate models. A deeper understanding of the molecular mechanisms underlying the functions of ADSS can provide a path to screening potential drugs and therapeutic strategies to treat ADSSL1-Myopathy.
Mentor(s):
Dr. Wendy Hanna-Rose
Major(s):
B.S. Biochemistry and Molecular Biology
Email:
Campus:
University Park