Development and Characterization of Magnesium-Doped Citrate-Based Biomaterials for Orthopedic Tissue Regeneration

Claire Tse

Various concentrations of Magnesium (Mg) were added to citrate-based biodegradable biomaterials enriched with glutamine to test Mg effects on bone regeneration. Material characterization studies included mechanical testing, long-term degradation (2-24 weeks), and rapid degradation (2-12 hours). Cell studies included cytotoxicity and proliferation studies in 100% degraded material solutions and on the biomaterial composite. Moderate Mg performed best in cytotoxicity and mechanical load bearing studies while the highest Mg concentration showed the most proliferation on biomaterial.

Major: 
Chemistry
Exhibition Category: 
Health and Life Sciences
Exhibition Format: 
Poster Presentation
Campus: 
University Park
Faculty Sponsor: 
Jian Yang
Poster Number: 
51823