From 2020 to 2023, the Greater Horn of Africa experienced a historic drought caused by five consecutive failed rainy seasons, leading to widespread food and water insecurity. Fingernail Cortisol Concentration (FCC) is a biomarker that reflects chronic stress over time, providing a long-term physiological measure. Studies have shown that food insecurity is significantly associated with lower FCC levels, while water insecurity is associated with higher FCC levels, highlighting the complex relationship between environmental stressors and biological stress responses.