Food insecurity（FI） is prevalent among Puerto Rican(PR) adults. In this study, we did a secondary data analysis on the Boston Puerto Rican Health Study Cohort（n=923）. We aimed to explore the longitudinal association between several psychosocial factors (Acculturation, depression, stress, social and community support, and life events) and FI status over 5 years. We found depression and stress may increase the risk of FI among PR adults.