Dopamine receptors are characterized as G-protein coupled receptors and can be further distinguished based on pharmacological properties. GPCR's are pharmacologically distinguished based on the stimulation or inhibition of cAMP. Parasteatoda tepidariorum have 6 dopamine receptors, DOP1, DOP2, and DOP3, the pharmacological properties of which are unknown, compared to humans 5 receptors. P. tepidariorum's extra receptor is thought to be due to genome duplication and performing cAMP assays will characterize the receptors compared to human receptors.