Characterization of Novel Delayed Hatching Phenotype observed in Caenorhabditis elegans

Vienna Louise Huso and Teniola Idowu

C. elegans containing a knock-out mutation in the nmrk-1 gene do not synthesize an enzyme known as nicotinamide riboside kinase which is involved in the synthesis of NAD+. Preliminary results suggest that a combination of this genetic mutation and an environmental stressor result in a novel delayed hatching phenotype exhibited in eggs laid by nmrk-1 mutants. Our results provide more details about the lifespan of unhatched embryos and the strength observed in this phenotype.

Major: 
Biochemistry and Molecular Biology
Exhibition Category: 
Health and Life Sciences
Exhibition Format: 
Poster Presentation
Campus: 
University Park
Faculty Sponsor: 
Wendy Hanna-Rose, Interim Department Head and Associate Professor of Biochemistry and Molecular Biology Department of Biochemistry and Molecular Biology
Poster Number: 
179