Plasmodium is a eukaryotic pathogen that still is responsible for 200 million infections and half a million deaths annually. An effective way to eliminate the parasite is to block its transmission from human to mosquito. Translational repression is a key process for the malaria parasite to be successfully transmitted, and thus may be targetable. I have developed molecular tools that can be used to investigate how the parasite regulates one important and abundant transcript, p25.