Antibiotic resistance is a current problem throughout the world, making bacterial infections more difficult to treat. Previously, a screen of 13,000 compounds was performed to test for potential antibiotics. Of those, two of the compounds were chosen for further testing. A minimum inhibitory assay, or MIC, will be performed using gram-negative bacteria, such as M. tuberculosis and S. flexneri. The MIC will determine the potential use of the compounds as an antibiotic against these bacteria.