Oxidative Stress Contributes to the Delayed Hatching of nmrk-1 Deficient C. elegans

Nicole Grace Laganke, Elizabeth Eberly and Michael DeGennaro

NAD+ is an essential molecule in biological processes such as metabolism and lifespan. Deficiencies in NAD+ lead to complications in the model organism C. elegans. We research a phenotype caused by a gene-environment interaction involving the riboside pathway of NAD+ synthesis. This delayed hatching phenotype occurs when nmrk-1 is knocked down and the animal is grown in oxidative stress environments. We seek to understand the contribution of environmental factors to the expression of delayed hatching.

Major: 
Biochemistry and Molecular Biology
Exhibition Category: 
Health and Life Sciences
Exhibition Format: 
Poster Presentation
Campus: 
University Park
Faculty Sponsor: 
Wendy Hanna-Rose, Interim Department Head, Biochemistry and Molecular Biology Associate Professor of Biochemistry and Molecular Biology Department of Biochemistry and Molecular Biology
Poster Number: 
167