NAD+ is an essential molecule in biological processes such as metabolism and lifespan. Deficiencies in NAD+ lead to complications in the model organism C. elegans. We research a phenotype caused by a gene-environment interaction involving the riboside pathway of NAD+ synthesis. This delayed hatching phenotype occurs when nmrk-1 is knocked down and the animal is grown in oxidative stress environments. We seek to understand the contribution of environmental factors to the expression of delayed hatching.
Oxidative Stress Contributes to the Delayed Hatching of nmrk-1 Deficient C. elegans
Nicole Grace Laganke, Elizabeth Eberly and Michael DeGennaro
Major:
Biochemistry and Molecular Biology
Exhibition Category:
Health and Life Sciences
Exhibition Format:
Poster Presentation
Campus:
University Park
Faculty Sponsor:
Wendy Hanna-Rose, Interim Department Head, Biochemistry and Molecular Biology Associate Professor of Biochemistry and Molecular Biology Department of Biochemistry and Molecular Biology
Poster Number:
167