The project I have been working on involved artificially creating insulin resistance, then reversing the inhibition. It was hypothesized that glucocorticoids cause insulin resistance through a mitogen-activated protein kinase (MAPK) regulated mechanism. By studying the insulin-resistant effects caused by the glucocorticoids, it can help us better understand the mechanism regulating the glucocorticoid-sensitive protein, REDD1, which creates an insulin resistance pathway. Insulin resistance and diabetes continues to be problematic in obese populations.