This study explored associations between environmental constructs and physical activity (PA) in rural cancer survivors (RCS). We found that more equipment in the home for exercise (OR=1.3, 95% CI:1.1-1.6), greater environmental support for PA (OR=1.3, 95% CI:1.1-1.6), lower street connectivity (OR=0.5, 95% CI:0.2-1.0), higher neighborhood aesthetics (OR=2.8, 95% CI:1.1-7.1), and the home environment (OR=1.3, 95% CI:1.1-1.6) were associated with meeting PA recommendations. Findings suggest the importance of the built environment in PA promotion among RCS.