Tumor excision, infected implants, and severe trauma can leave behind gaps in bones so large that they are irreparable by the body. Bone grafts and scaffolds can be used to bridge the defect, but thus far, none are porous enough to permit healing throughout the entire length of the defect while also being strong enough to bear loads. Here, steps are taken to develop a two-part scaffold with a load-bearing exterior and highly permeable interior.
Biphasic Bone Scaffolds for Regeneration in Large Defects
by Maria Rose Hudock
Heritage Hall, HUB-Robeson Center