Candidate Genes for Wolbachia Blocking of Dengue Virus In Aedes aegypti Cells

by Joash Makalani Lake

Wolbachia pipientis is a bacterial endosymbiont found in many insects. Since its introduction into the mosquito species Aedes aegypti, Wolbachia has been found to decrease the replication of dengue virus - thus hampering its transmission to humans. However, the mechanism for this 'viral blocking' is unknown. Here I present data on the transcription of candidate blocking genes in Aedes aegypti cells during infection or co-infection of Wolbachia and dengue virus as measured by qRT-PCR

Major: 
Biochemistry and Molecular Biology
Exhibition Category: 
Health and Life Sciences
Exhibition Format: 
Poster Presentation
Campus: 
University Park
Faculty Sponsor: 
Elizabeth McGraw
Location: 
Alumni Hall, HUB-Robeson Center
Poster Number: 
213