Joash Makalani Lake
Wolbachia pipientis is a bacterial endosymbiont found in many insects. Since its introduction into the mosquito species Aedes aegypti, Wolbachia has been found to decrease the replication of dengue virus – thus hampering its transmission to humans. However, the mechanism for this ‘viral blocking’ is unknown. Here I present data on the transcription of candidate blocking genes in Aedes aegypti cells during infection or co-infection of Wolbachia and dengue virus as measured by qRT-PCR