An examination of hippocampal microglia and anxiety behavior after chronic peri-adolescent asthma

by Kerri Jean Schopf

Asthma is a chronic allergic disease that is often comorbid with anxiety disorders. The hippocampus in the brain is involved in emotion regulation and has a high density of microglia - immune cells that become active during immune responses. In a mouse model, we determined whether asthma symptoms during development led to increased anxiety behavior and microglial activation in the hippocampus using gene expression, and staining. The results support the comorbidity between asthma and anxiety.

Major: 
Biology
Exhibition Category: 
Health and Life Sciences
Exhibition Format: 
Poster Presentation
Campus: 
University Park
Faculty Sponsor: 
Sonia Cavigelli
Location: 
Alumni Hall, HUB-Robeson Center
Poster Number: 
115