Ribosomes are crucial to cellular function and development, as they are responsible for translation of mRNA to produce proteins that are vital to life.  In Drosophila melanogaster neurons, ribosomes accumulate in the soma and dendritic branch points, but not the long axon.  This body of work aimed to uncover how exactly ribosomes are being localized to dendritic branch points, and it was found that this is dependent on minus-end-out microtubule polarity.