Microtubules have an inherit polarity allowing for proper neuronal function. Y-Tubulin localization to the branch points of dendrites in class I DA neurons in Drosophila is key for the nucleation and regulation of microtubules. The proteins that constitute the Wnt-signaling pathway help localize Y-Tubulin to the branch points of dendrites. A protein, outside of the Wnt proteins, Cdk5 has shown a phenotype for localizing Y-Tubulin, and I am investigating the possible pathways for this localization.