Antibiotic resistance is becoming a serious health issue that needs to be fixed. Since most current antibiotics come from natural products, they are a likely source of new antibacterial agents.  Crude extracts were extracted and purified from several plants. These extracts were analyzed and found to have antibacterial properties against  B. anthracis and E. coli. Future screening will involve testing for inhibition against the trans-translation pathway, a ribosome rescue mechanism found only in bacteria.