Within the U.S., the burden of cardiovascular disease (CVD) is greatest among African American men for distinct reasons. African American men experience the highest rates of hypertension and are the least likely to receive effective treatment. The American Heart Association acknowledges isometric handgrip (IHG) training as alternative approach towards regulating blood pressure and requested more trials in diverse populations. We aim to investigate the effects of IHG training on blood pressure within African American Men.