Spontaneous Seizure-Associated Spreading Depolarization Relationship with Heart Rate in a Chronic Rodent Model of Temporal Lobe Epilepsy

Carlos Curay
Previous studies assumed that Spreading Depression and seizure dynamics were closely associated. This correlation is significant because it supports the framework that Sudden Unexpected Death in Epileptic Patients (SUDEP) is mediated by SD invasion of brainstem. The Gluckman lab has consistently found SD alongside seizures in a tetanus toxin model. Now, the group is looking at EKG data alongside SD data as a potential explanation for SUDEP, which could ultimately lead to new treatment approaches.
Major: 
Biology
Exhibition Category: 
Health and Life Sciences
Exhibition Format: 
Poster Presentation
Campus: 
University Park
Faculty Sponsor: 
Bruce Gluckman
Location: 
Heritage Hall, HUB-Robeson Center
Poster Number: 
355