Rosalie Sowers
Rosalie Sowers
The Mixed Lineage Leukemia (MLL) complex plays a key role in gene regulation by covalently modifying the nucleosome packaging unit of DNA. However, we do not understand how the MLL enzyme works on its nucleosome substrate. I am working to determine the structure of the 500 kDa MLL/nucleosome complex by X-ray crystallography to provide insight into its molecular mechanism and the basis for its association with leukemia
Major:
BMB
Exhibition Category:
Health and Life Sciences
Exhibition Format:
Poster Presentation
Campus:
University Park
Faculty Sponsor:
Song Tan
Location:
Heritage Hall, HUB-Robeson Center
Poster Number:
319