by Geneva Flarend
Antibiotic resistance is an international threat to human health. The diverse microbiome of soil has made it a prime candidate for antibiotic discovery. A crude extract isolated from a soil sample showed broad-spectrum antibacterial activity. This extract was fractionated and screened for activity against the translation and sE pathways in bacteria in vitro and in vivo. Most of the fractions obtained inhibited both pathways, providing candidates with antibiotic properties.
Biochemistry and Molecular Biology (Cellular Biology)
Health and Life Sciences