Antibacterial natural product inhibits in vivo translation and sigma E pathways

by Geneva Flarend
Antibiotic resistance is an international threat to human health. The diverse microbiome of soil has made it a prime candidate for antibiotic discovery. A crude extract isolated from a soil sample showed broad-spectrum antibacterial activity. This extract was fractionated and screened for activity against the translation and sE pathways in bacteria in vitro and in vivo. Most of the fractions obtained inhibited both pathways, providing candidates with antibiotic properties.
Biochemistry and Molecular Biology (Cellular Biology)
Exhibition Category: 
Health and Life Sciences
Exhibition Format: 
Poster Presentation
University Park
Faculty Sponsor: 
John Alumasa
Poster Number: