by Sarah Watkins
Since the late 1920s, Antimicrobial compounds have been abused and misused resulting in the development of resistance in bacteria. Through unique methods of isolation, purification, and analysis, I addressed this issue by extracting antimicrobial compounds from soil near Tytoona cave in Pennsylvania. The crude extract was fractionated and select fractions were shown to be inhibitors of translation and the sE pathway in Escherichia coli.
Biochemistry and Molecular Biology