The effect of the small RNA RyhB on the structure of its mRNA targets

by Samantha Grecco

RyhB is a sRNA in Escherichia coli that is expressed under iron-limiting conditions and regulates the iron sparing response. The majority of RyhB targets have not been characterized and the role of RNA structure in the sRNA-mRNA interactions is unknown. It is hypothesized that the target mRNA secondary structure influences the ability of RhyB to interact and that the interaction may induce a structural rearrangement that alters gene expression.

Major: 
Biochemistry and Molecular Biology
Exhibition Category: 
Physical Sciences
Exhibition Format: 
Poster Presentation
Campus: 
University Park
Faculty Sponsor: 
Philip Bevilacqua
Poster Number: 
15594