Metal organic framework materials (MOFs) are coordination polymers that vary in shape and size. With increasing availability, it is speculated MOFs can be synthesized capable of absorbing biomedically active substances, such as cannabidiol (CBD). Recently, cannabinoids have been decriminalized leading to a need for technology in identification and purification. From this investigation, MOF MIL-53(Al) will potentially absorb cannabinoids, while maintaining structural integrity through extraction. Theoretical calculations confirm this for different types of MIL-53(Al).