Bifidobacterium adolescentis L2-32 N-terminal acylation lipoprotein characterization and TLR activation

Lipoproteins are important structures that allow the bacteria to survive. When it comes to human health, these lipoproteins act as Pathogen-associated molecular patterns, or PAMPS, that can activate Toll-Like-Receptors of the innate immune system. Lipoprotein structures are determined by their N-Terminal acylation which is controlled by different enzymes. Bifidobacterium adolescentis strain L2-32 has an unknown lipoprotein that is being determined by mass spectrometry and has been found to activate TLR 2 receptors.