CD36 Overexpression Induces Epithelial to Mesenchymal Transition

by Ryan Swartz, Nikhita Arunprakash, Sanjana Bhawnani, My-Hoa Do and Shalini Shah

The CD36 scavenger receptor is overexpressed in some cancers, but how this impacts tumor cell functions is not well understood. This project aims to explore how CD36 influences epithelial to mesenchymal transition and associated metastasis markers. Using a doxycycline-inducible system for overexpression of CD36 and examination of multiple markers of the epithelial to mesenchymal transition, we show that CD36 increases key markers of a mesenchymal phenotype.

Major: 
Biology
Exhibition Category: 
Health and Life Sciences
Exhibition Format: 
Poster Presentation
Campus: 
University Park
Faculty Sponsor: 
Emily Bell
Poster Number: 
16812