Clostridium symbiosum lipoprotein structure and toll-like receptor (TLR) activity

by Katie Alesi

Over the last two semesters, I have studied lipoprotein structure in Clostridium symbiosum. Lipoprotein structure is important in bacteria, as it responsible for various factors such as virulence, metabolism, antibiotic resistance, and more. I have isolated the lipoproteins from the other cell components, including supernatant proteins, and am currently using mass spectrometry to analyze these proteins. Additionally, TLR-2 activity was tested using pasteurized bacterial cells and HEK-Blue hTLR2 cells to measure inflammation.

Major: 
Microbiology
Exhibition Category: 
Health and Life Sciences
Exhibition Format: 
Poster Presentation
Campus: 
University Park
Faculty Sponsor: 
Timothy Meredith
Poster Number: 
16741