CD36 is a major mediator of fatty acid uptake that has been found to be overexpressed in several types of cancer, but is poorly undersood when it comes to tumor progression. We want to investigate whether CD36 contributes to aggressive cancer features. We overexpressed CD36 in HeLa and MDCK epithelial cells. We found that CD36 increased migration and expression of mesenchymal cell markers, supporting a potential role in increasing invasion and metastasis in cancer cells.
Dox Induced CD36 Promotes Cell Migration by Contributing to Mesenchymal Phenotypes
Tealine Williams, Sydney Danso, Emily Hassett, Sam Barnett and Ahnika Hay
Major:
Biological Sciences and Health Professions
Exhibition Category:
Health and Life Sciences
Exhibition Format:
Poster Presentation
Campus:
University Park
Faculty Sponsor:
Emily Bell
Poster Number:
16793