Ritika Sagar and Shweta Marathe
In children, behavioral inhibition (i.e. avoidance of novelty) is a strong predictor of later anxiety disorders. Resting-state brain functional connectivity has been related to both behavioral inhibition and anxiety disorders. For example, in anxiety disorder, patients have decreased default mode network (DMN) and fronto-parietal network (FPN) connectivity – two systems associated with emotion regulation and cognitive control. In this study, we examined whether a rodent model of BI shows similar altered DMN/FPN connectivity.