Battle of the Breast Cancer Cells: The Effects of Ras Oncogene Overexpression on Entosis.

by Lindseigh Ashbridge, Brady Lim and Oriana Xhaferi

Entosis is a complex mechanism of cell death in which a living cell ingests another living cell. Previous research indicates cells undergo entosis as a result of glucose starvation and as a method of obtaining nutrients. We studied various cell lines and Ras oncogenic mutations to determine characteristics that may promote entosis in cancer cells. Our findings support the hypothesis that Ras oncogenic overexpression, along with other factors, promote entosis.

Major: 
Biochemistry and Molecular Biology
Exhibition Category: 
Health and Life Sciences
Exhibition Format: 
Poster Presentation
Campus: 
University Park
Faculty Sponsor: 
Sampurna Sattar
Poster Number: 
51861