Chromatin Remodeler Modulator CDCA7L –Properties & Structural Analysis

by Shawn Hu

Cell Division Cycle Associated 7 Like is a transcription factor mediated by c-Myc. Mutations in CDCA7L or LSH1 can result in DNA methylation defection4, one of the leading causes of Immunodeficiency-Centromeric Instability-Facial Anomalies Syndrome and several cancers. In this research study, CDCA7L was purified from the E. Coli expression system, and its structural properties were further analyzed with biochemical assays and Transmission Electron Microscope.

Major: 
Biochemistry and Molecular Biology, Structural Biology
Exhibition Category: 
Health and Life Sciences
Exhibition Format: 
Poster Presentation
Campus: 
University Park
Faculty Sponsor: 
Jean-Paul Armache
Poster Number: 
51885