Claire Tse
Various concentrations of Magnesium (Mg) were added to citrate-based biodegradable biomaterials enriched with glutamine to test Mg effects on bone regeneration. Material characterization studies included mechanical testing, long-term degradation (2-24 weeks), and rapid degradation (2-12 hours). Cell studies included cytotoxicity and proliferation studies in 100% degraded material solutions and on the biomaterial composite. Moderate Mg performed best in cytotoxicity and mechanical load bearing studies while the highest Mg concentration showed the most proliferation on biomaterial.