The role of the human gut microbiomes has begun to garner more research interest, with microbial composition being implicated in diseases from allergies to depression. However, the role of fungal communities in the human gut microbiome remains understudied compared to bacterial counterparts. To address these gaps, I use a combination of wet-lab and computational techniques to determine if differential abundances of fungal communities in the human gut are correlated with differences in human gene expression.