During 2017, a free-ranging, 3-year-old female, elk (Cervus elaphus), with suspect piebaldism, was found emaciated and unable to stand. The cow was euthanized and upon necropsy had a large, multilobular, dark red mass in the oral cavity extending from the caudal soft palate and a smaller dark red mass in the right caudal lung lobe. Cytologic and histopathologic examination of the masses diagnosed malignant melanoma, which was confirmed with immunohistochemistry.