Annabelle Bernard
Various Drosophila neurons prune and regrow their dendrites during metamorphosis, induced by ecdysone. Neurons can be injured in many ways and require regenerative pathways. A deficiency screen showed no candidates for dendrite regeneration, but two lines show decreased branching. Both deficiencies have the same endpoint containing a UAS insertion in the gene for the ecdysone induced protein 93f. The UAS insertion is being activated by Gal4, causing expression of E93, possibly leading to premature pruning.