Conserved RCK Domains Important for Sulfate Transport

YfbS is a sulfate transporter found in many marine Vibrionaceae. It functions to import sulfate from the marine environment for the bacteria to grow and survive. YfbS contains two RCK domains, a broad class of domains known to control nutrient import. While RCK domains are well characterized in K+ channels, their function and mechanism remain unclear in YfbS. This work shows that the RCK domains are important for YfbS function of importing sulfate.