Asthma is linked to multiple comorbidities (Heckking et al. 2017). Interestingly, the top five comorbidities of asthma are also linked to sleep disorders (Madrid-Valero et al. 2020). We hypothesized that these disorders may share common underlying mechanisms and we reviewed the literature to determine if there is support for this idea. Shared mechanisms could be clinically-relevant leading to improvements in treating both disorders (Lee et al., 2017); sleep interventions should be considered when treating asthma.