Despite its prevalence, endometriosis often goes undiagnosed due to a lack of awareness, symptom dismissal, and absence of point of care detection device. Approximately 10% of women (especially young adults and women in their mid-thirties) can be diagnosed with mild to severe form of Endometriosis. iInstead of invasive diagnostic procedures like laparoscopy, our aim is to utilize menstrual blood as a non-invasive diagnostic tool for endometriosis. Using a lateral flow assay method, a point-of-care diagnosis of endometriosis can be achieved using menstrual effluent. This work specifically targets specific upregulated protein biomarker present in menstrual blood.