Hannah Bauer
Streptococcus mitis is an opportunistic pathogen that is resistant to common antibiotics. The Keiler Lab has identified 46 small molecule inhibitors that block the trans-translation pathway in bacteria. KKL-35, a small molecule inhibitor, was found to be active at 2.5 µM in a S. mitis culture. An in vitro trans-translation assay would be able to confirm if MBX-4204 inhibits trans-translation in S. mitis, and therefore would be a good antibiotic candidate.
Major:
Biochemistry and Molecular Biology
Exhibition Category:
Health and Life Sciences
Exhibition Format:
Poster Presentation
Campus:
University Park
Faculty Sponsor:
Ken Keiler
Poster Number:
93