Methods Investigation for Inducing Variation of Free-Tubulin Within Branchpoints of ddaE Neurons

Madison Michelitch

The disfunction of microtubules has been linked to developmental and neurodegenerative pathologies. Microtubules are comprised of tubulin subunits and are a part of the cytoskeleton. In healthy neurons, they serve to maintain cellular shape and facilitate polarized transport for neurotransmitters, proteins, organelles, and nutrients for the cell. The molecular mechanisms behind the stability of microtubules in neurons are not well understood. We pose two methods of varying tubulin concentration to investigate its effects on microtubules. 

Major: 
Biochemistry & Molecular Biology
Exhibition Category: 
Health and Life Sciences
Exhibition Format: 
Oral Presentation
Campus: 
University Park
Faculty Sponsor: 
Melissa Rolls
Poster Number: 
205