Blood flow will be mimicked using an in vitro flow loop and ultrasound, a diagnostic tool used for thrombi and emboli identification, records the formation of emboli in real-time in a bovine vessel.  Afterwards, emboli development will be analyzed and quantified computationally.   Little is understood about emboli development, therefore, techniques for studying real-time formation would be crucial for prevention. 

In the Rolls lab we look at protein localization in the model organism drosophila. Proteins have key roles within organisms and are vital for the survival of organisms. Without the proper proteins in the cell neurons lose their ability to properly function in the cell. By using different RNAi fly lines various proteins can be knocked down and the effects it has on the organism can be observed using different microscopy techniques. 

Finding a new combination of two-dimensional material and bio-molecules can allow for a greater biosensor diversity, allowing biosensors to be used in more applications.

The Role of Sign and Symbol in Contemporary Painting

Few studies have examined how individual traits affect problem-solving behaviors in engineering design settings. Our study examined the Preferences for Creativity Scale (PCS) and Kirton’s Adaption-Innovation inventory (KAI), and compared it to creativity of the ideas generated and selected. Results show PCS predicted participants’ propensity for creative concept selection. Specifically, team centrality and influence and risk tolerance significantly contributed. KAI predicted generation of creative and original ideas, and propensity for quality concept selection.

Dissolved oxygen is an integral part of marine life used by all organisms for respiration. Water samples from the N. Atlantic and Caribbean were collected using a hydrocast during a SEA oceanographic cruise measuring dissolved oxygen and chlorophyll-a concentrations. Chlorophyll maximums correlated with increasing DO concentrations.  Primary production was greatest at a depth similar in all locations. The connection between dissolved oxygen and chlorophyll-a helps determine the location of production in the ocean.

The objective of this research is to understand the origins photo-spin current and obtain the current measurements along longitudinal and transverse direction of metasurface. The phase gradient and surface plasmon property of metasurface enhance the spin-orbit interaction, which allowing more observations and analyzations in photon spin manipulating applied in electronic-optical devices. For this research, we reproduce the interaction by employing circular polarization light normally impinging on metasurface and measure the current induced using Lock-in amplifier.

Antibiotic resistance is a growing issue that leads to the ineffectiveness of drugs that treat bacterial infections. New investigations are currently underway to determine the effectiveness of helper compounds, which include a range of drug classes, particularly antihistamines. Antihistamines oppose the constitutive activity of histamine receptors, which function to produce biological responses. The antihistamine, Azelastine, possesses antibacterial activity by altering bacterial membrane permeability. 

This research shows an Ohmic contact and a Shockley diode with given semiconductors to observe Ohmic and Shockley behaviors. In one evaporation there will be coating of a N type wafer, and a P type wafer with aluminum using the same shadow mask. Measurements will be made between current and voltage at differing frequencies.

The food security for India’s growing population is threatened by the decline in freshwater resources due to unsustainable consumption for irrigation. This issue is acute in parts of Punjab, India, where small landholders produce a major quantity of India’s food. This state-wide coupled hydrologic, agricultural, and economic model of Punjab was built to assess and optimize crop choice scenarios based on farmer income, food production, and hydrologic system constraints.

Simultaneous axon and dendrite injury is likely to occur in response to stroke and traumatic brain injury. Although axon regeneration has been well characterized and dendrites are known to regenerate via an undefined mechanism that is distinct from that of axons, concurrent axon and dendrite has not been well studied. We aim to induce injury in both axons and dendrites to characterize how the pathways for axon and dendrite regeneration interact with one another. 

In 1942, Argentine composer, Angel Lasala wrote Poema del Pastor Coya. “Pastor Coya” is a shepherd among the indigenous people in northern Argentina. The first movement depicts the shepherd’s lifestyle. The second movement emulates a traditional Andean wooden flute. The final movement is a celebration—melodies and rhythms heard at dances the shepherds used to attend. In 2017, I traveled to the northern Provinces of Jujuy and Salta and studied the melodies in this piece.

Many neurological disorders are characterized by loss of different types of neurons. Reprogramming is a process in which glial cells in the brain are changed into functional neurons. Two aspects are reprograming by small molecules to induce the Gabaergic Phenotype and reprogramming using viruses that encode transcription factors to induce a dopaminergic phenotype. A third aspect is exploring the mechanism by which NeuroD1, a transcription factor, reprograms glial cells into functional Glutamatergic neurons.

Endocarditis is a bacterial infection that has a high mortality rate because the molecules of antibiotics are too large to penetrate the biofilm of the bacteria. Low temperature plasma (LTP), currently used to sterilize medical equipment, will be created by running 30,000V through two electrodes over a 20 nanosecond time span in either water, saline, fetal bovine serum, and eventually human blood.